OCS

Oculis Holding AG

Fundamental data last updated:November 6, 2026

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company profile

SECTOR

Healthcare

industry

Biotechnology

Exchange

NASDAQ

County of HQ

CH

Next Earnings Date

Pending Announcement

Business Summary

Oculis Holding AG is a biopharmaceutical company in the clinical development stage, specializing in the creation of innovative eye drop medications for various ocular conditions, addressing both the anterior and posterior segments of the eye. A key asset in its therapeutic portfolio is OCS-01, a topical formulation of dexamethasone, currently progressing through Phase 3 clinical trials for the management of diabetic macular edema. Additionally, OCS-02, a topically administered biological candidate, is engaged in Phase 2b clinical studies to treat keratoconjunctivitis sicca, commonly known as dry eye disease. The company is also advancing OCS-05, an innovative neuroprotective agent, which targets acute optic neuritis and an array of other neuro-ophthalmic disorders, including glaucoma, diabetic retinopathy, geographic atrophy, and neurotrophic keratitis. This enterprise maintains its headquarters in Zug, Switzerland.

 


VALUATION

P/E

-4.97

Market Cap ($M USD)

$518.48M

Forward P/E

10.15

PEG

0.38

PRICE TO SALES

1764.37

PRICE TO BOOK

1.94

EV / EBITDA

-5.50

5-Year Average P/E

Free Cash Flow Yield

-15.41%

DCF Value

$1.80

Graham Number

N/A

Price to FCF

-6.49

EV to FCF

-6.53

Earnings Yield

-18.68%

FCF Yield

-15.41%

DIVIDEND

Yield

0.00%

Annual Payout

$0.00

Payout Ratio

0.00%

Consecutive Years of Dividend Growth

5-Year Dividend Growth Rate

Financial Health & Profitability

Earnings Per Share

-$1.30

Next Year EPS Growth Estimate

-$1.54

Next Year Revenue Growth Estimate

$840,884.00

Return on Equity (ROE)

-42.92%

FREE CASH FLOW

Operating Margin

-35874.24%

Debt-to-Equity

0.01

Piotroski F-Score

4

Altman Z-Score

5.46

Return on Invested Capital (ROIC)

-38.94%

Current Ratio

8.35

Quick Ratio

8.35

Net Debt to EBITDA

-0.03

Interest Coverage

-93.99

Gross Profit margin

35.21%

FCF PER SHARE

$-1.08

REVENUE PER SHARE

$0.00

Gainseekers Quantitative Analysis

Summary

OCS Oculis Holding AG’s valuation is a paradox. Despite a staggering market cap, its DCF value is a mere fraction of its snapshot price, suggesting significant overvaluation. The Forward P/E of 11.92 hints at optimism, yet the negative earnings yield and ROIC paint a grim picture of profitability. The Altman Z-score of 19.07 indicates financial safety, but the market seems to be pricing in perfection without the earnings to back it up. This stock is a high-risk gamble on future growth rather than a value play.

AI Exposure / Tech Reliance

Operating in the biotechnology sector, OCS is well-positioned to leverage AI advancements in drug discovery and personalized medicine. The industry is ripe for technological disruption, and companies like OCS can capitalize on AI to streamline R&D processes. However, execution will be key in translating tech potential into tangible results.

The Bull Case

For the bold investor, OCS offers a tantalizing growth narrative. The Forward PEG ratio of 0.0467 is a beacon for GARP investors, signaling potential undervaluation relative to growth. Despite a negative FCF yield, the company's low debt-to-equity ratio and high current ratio suggest robust financial health. The Piotroski F-Score of 3 is modest, but the potential for explosive sales growth could justify a speculative position.

The Bear Case

OCS faces daunting structural risks. The Price/Sales ratio is astronomical, indicating the market is pricing in massive future sales that may never materialize. With a negative operating margin of -16,254.38%, the company hemorrhages cash, and its proximity to the 52-week high suggests technical overextension. The negative gross profit margin further underscores the lack of pricing power and operational efficiency.

Market Sentiment & Smart Money

Short Interest %

Analyst Consensus

Buy

Average Analyst Price Target

$36.75

Institutional Ownership %

1-Year Beta

0.23

Insider Buying % (6 Mo)

Distance to 52-Week High

309.57%

Distance to 52-Week Low

15.54%

EARNINGS SURPRISE %

58.33%

50-DAY SMA

$9.95

200-DAY SMA

$18.97

⚠️ Financial Disclaimer:
This content is for informational purposes only and is not financial advice. Information may be delayed or inaccurate. We may earn a commission from partner links.