ONC

BeOne Medicines Ltd.

Fundamental data last updated:June 19, 2026

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company profile

SECTOR

Healthcare

industry

Medical - Pharmaceuticals

Exchange

NASDAQ

County of HQ

US

Next Earnings Date

08/05/2026

Business Summary

BeOne Medicines, formerly known as BeiGene, is a global oncology company focused on discovering, developing, and commercializing innovative cancer therapies. Founded in 2010 and headquartered in Cambridge, Massachusetts—with operations spanning over 45 countries across six continents—the company rebranded as BeOne in late 2024 and redomiciled to Basel, Switzerland in 2025. BeOne has established itself as a leader in immuno-oncology and targeted therapies, with key assets including Tevimbra (tislelizumab), a PD-1 monoclonal antibody approved for multiple cancer indications globally, and Brukinsa (zanubrutinib), a Bruton's tyrosine kinase (BTK) inhibitor that surpassed $1.3 billion in annual sales and is approved in major markets such as the U.S., Europe, and China. The company’s strategy combines internal R&D with the development of assets sourced from external partnerships, driving a robust pipeline across hematologic malignancies and solid tumors.

 


VALUATION

P/E

809.04

Market Cap ($M USD)

$30.89B

Forward P/E

15.43

PEG

0.00

PRICE TO SALES

6.53

PRICE TO BOOK

10.87

EV / EBITDA

43.40

5-Year Average P/E

Free Cash Flow Yield

2.93%

DCF Value

$-4480.00

Graham Number

$5.16

Price to FCF

34.13

EV to FCF

31.60

Earnings Yield

0.99%

FCF Yield

2.93%

DIVIDEND

Yield

0.00%

Annual Payout

$0.00

Payout Ratio

0.00%

Consecutive Years of Dividend Growth

5-Year Dividend Growth Rate

Financial Health & Profitability

Earnings Per Share

$0.36

Next Year EPS Growth Estimate

$18.73

Next Year Revenue Growth Estimate

$1.04T

Return on Equity (ROE)

12.10%

FREE CASH FLOW

Operating Margin

11.96%

Debt-to-Equity

0.46

Piotroski F-Score

7

Altman Z-Score

5.42

Return on Invested Capital (ROIC)

10.20%

Current Ratio

3.64

Quick Ratio

3.27

Net Debt to EBITDA

-3.47

Interest Coverage

12.79

Gross Profit margin

87.17%

FCF PER SHARE

$0.76

REVENUE PER SHARE

$4.00

Gainseekers Quantitative Analysis

Summary

ONC BeOne Medicines Ltd. presents a perplexing valuation scenario. Despite a staggering Price/Earnings ratio, the Forward P/E suggests a more reasonable growth expectation. The market seems to misprice it relative to its DCF Value, which is deeply negative, and the Graham Number, indicating potential overvaluation. However, the Altman Z-score of 5.55 signals robust financial health, and the Earnings Yield is low, suggesting limited immediate returns. This stock is a complex puzzle of high growth potential and current overvaluation.

AI Exposure / Tech Reliance

Operating in the Medical - Pharmaceuticals sector, ONC is well-positioned to leverage AI for drug discovery and personalized medicine. The industry is ripe for technological integration, enhancing research efficiency and patient outcomes. This adaptability could drive future growth and innovation.

The Bull Case

For the discerning GARP investor, ONC offers compelling strengths. With a ROIC of 10.20% and a Piotroski F-Score of 7, the company demonstrates efficient capital allocation and solid financial health. Its Free Cash Flow Yield, although modest, indicates some cash generation capability. The impressive gross profit margin of 87.17% underscores its pricing power and operational efficiency, making it an attractive prospect for those seeking growth at a reasonable price.

The Bear Case

Despite its strengths, ONC faces significant structural risks. The Price/Book ratio of 11.04 and Price/Sales of 6.63 suggest the stock is trading at a premium, potentially overextended. Its Earnings Yield is a mere 0.98%, offering scant immediate returns. Additionally, the stock's proximity to its 52-week high raises concerns about technical overextension, making it vulnerable to market corrections.

Market Sentiment & Smart Money

Short Interest %

Analyst Consensus

Buy

Average Analyst Price Target

$397.89

Institutional Ownership %

1-Year Beta

0.50

Insider Buying % (6 Mo)

Distance to 52-Week High

33.28%

Distance to 52-Week Low

17.22%

EARNINGS SURPRISE %

168.49%

50-DAY SMA

$301.31

200-DAY SMA

$321.28

⚠️ Financial Disclaimer:
This content is for informational purposes only and is not financial advice. Information may be delayed or inaccurate. We may earn a commission from partner links.