ANAB

AnaptysBio, Inc.

Fundamental data last updated:September 6, 2026

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company profile

SECTOR

Healthcare

industry

Biotechnology

Exchange

NASDAQ

County of HQ

US

Next Earnings Date

Pending Announcement

Business Summary

AnaptysBio, Inc., a clinical stage biotechnology company, engages in developing therapeutic product candidates for inflammation and immuno-oncology indications. Its products include Imsidolimab, an antibody that inhibits the interleukin-36 receptor (IL-36R) for the treatment of various dermatological inflammatory diseases; Rosnilimab, an anti-PD-1 agonist antibody program designed to augment PD-1 signaling through rosnilimab treatment to suppress T-cell driven human inflammatory diseases; and ANB032, an anti-BTLA modulator antibody applicable to human inflammatory diseases associated with lymphoid and myeloid immune cell dysregulation. The company also focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has a collaboration and license agreement with GlaxoSmithKline, Inc. and Bristol-Myers Squibb; and license agreements with United Kingdom Research and Innovation, as well as Millipore Corporation. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.

 


VALUATION

P/E

-61.07

Market Cap ($M USD)

$2.46B

Forward P/E

7.97

PEG

0.01

PRICE TO SALES

10.58

PRICE TO BOOK

128.34

EV / EBITDA

46.64

5-Year Average P/E

Free Cash Flow Yield

0.18%

DCF Value

$-307.91

Graham Number

N/A

Price to FCF

557.69

EV to FCF

564.24

Earnings Yield

-1.64%

FCF Yield

0.18%

DIVIDEND

Yield

0.00%

Annual Payout

$0.00

Payout Ratio

0.00%

Consecutive Years of Dividend Growth

5-Year Dividend Growth Rate

Financial Health & Profitability

Earnings Per Share

-$0.93

Next Year EPS Growth Estimate

$7.15

Next Year Revenue Growth Estimate

$473.45M

Return on Equity (ROE)

442.91%

FREE CASH FLOW

Operating Margin

17.56%

Debt-to-Equity

0.38

Piotroski F-Score

5

Altman Z-Score

3.42

Return on Invested Capital (ROIC)

14.17%

Current Ratio

7.58

Quick Ratio

7.58

Net Debt to EBITDA

0.54

Interest Coverage

0.49

Gross Profit margin

116.42%

FCF PER SHARE

$0.15

REVENUE PER SHARE

$8.10

Gainseekers Quantitative Analysis

Summary

The market seems to be mispricing AnaptysBio, Inc. significantly. With a DCF value deep in the negative and a Graham Number unavailable, the stock’s valuation appears stretched. However, the Forward P/E of 9.52 suggests optimism for future earnings, contrasting sharply with its current negative Earnings Yield. The Altman Z-score of 4.77 indicates financial stability, hinting at a low risk of bankruptcy. This mixed bag of metrics paints a picture of a company with potential growth but currently overvalued by traditional measures.

AI Exposure / Tech Reliance

In the rapidly evolving biotechnology sector, AnaptysBio is well-positioned to leverage AI advancements. The industry’s inherent reliance on cutting-edge technology for drug development aligns with AI's capabilities in data analysis and predictive modeling. This synergy could enhance their R&D efficiency and accelerate innovation.

The Bull Case

For the discerning GARP investor, AnaptysBio offers compelling reasons to buy. The ROIC of 14.7% demonstrates robust capital efficiency, while a Piotroski F-Score of 5 suggests moderate financial health. Despite a modest FCF Yield, the impressive operating margin of 20.42% indicates strong pricing power. These metrics collectively highlight a company capable of generating substantial returns on invested capital.

The Bear Case

Yet, the stock is not without its pitfalls. The Price/Book ratio of 51.78 and Price/Sales of 12.74 suggest a valuation bubble, with the stock trading at a premium. Its proximity to the 52-week high raises concerns about technical overextension. Additionally, the negative EPS and high EV to EBITDA ratio of 45.58 underscore challenges in profitability and cash flow generation.

Market Sentiment & Smart Money

Short Interest %

Analyst Consensus

Buy

Average Analyst Price Target

$83.14

Institutional Ownership %

1-Year Beta

0.48

Insider Buying % (6 Mo)

Distance to 52-Week High

26.90%

Distance to 52-Week Low

80.00%

EARNINGS SURPRISE %

-475.00%

50-DAY SMA

$53.26

200-DAY SMA

$33.01

⚠️ Financial Disclaimer:
This content is for informational purposes only and is not financial advice. Information may be delayed or inaccurate. We may earn a commission from partner links.