AZN

AstraZeneca PLC

Fundamental data last updated:September 6, 2026

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company profile

SECTOR

Healthcare

industry

Drug Manufacturers - General

Exchange

NYSE

County of HQ

GB

Next Earnings Date

Pending Announcement

Business Summary

AstraZeneca PLC operates as a global biopharmaceutical leader, dedicated to the entire process of bringing prescription medicines to market, from their initial discovery and development through manufacturing and commercialization. The company's extensive portfolio of treatments, including prominent examples like Tagrisso, Farxiga, and Symbicort, addresses critical areas such as cardiovascular, renal, metabolic, and oncological conditions. Furthermore, it provides essential solutions for COVID-19 and various rare diseases, with products like Vaxzevria and Soliris. AstraZeneca engages with primary and specialty care physicians worldwide, facilitating distribution through a robust network of representatives and local offices across the United Kingdom, continental Europe, the Americas, Asia, Africa, and Australasia. The firm actively drives innovation through strategic collaborations, partnering with entities such as Neurimmune AG for the development and commercialization of NI006, BenevolentAI for systemic lupus erythematosus drug discovery, Lunit for AI-powered digital pathology risk assessment in NSCLC, and Absci Corporation for AI-driven oncology target identification. Founded in 1992, the company was initially known as Zeneca Group PLC, subsequently rebranding to AstraZeneca PLC in April 1999, and maintains its headquarters in Cambridge, United Kingdom.

 


VALUATION

P/E

28.18

Market Cap ($M USD)

$294.91B

Forward P/E

11.26

PEG

0.08

PRICE TO SALES

4.90

PRICE TO BOOK

6.29

EV / EBITDA

15.79

5-Year Average P/E

Free Cash Flow Yield

2.60%

DCF Value

$556.23

Graham Number

$68.12

Price to FCF

38.46

EV to FCF

41.87

Earnings Yield

3.51%

FCF Yield

2.60%

DIVIDEND

Yield

1.65%

Annual Payout

$3.16

Payout Ratio

46.98%

Consecutive Years of Dividend Growth

5-Year Dividend Growth Rate

Financial Health & Profitability

Earnings Per Share

$6.75

Next Year EPS Growth Estimate

$16.88

Next Year Revenue Growth Estimate

$82.97B

Return on Equity (ROE)

22.41%

FREE CASH FLOW

Operating Margin

23.53%

Debt-to-Equity

0.61

Piotroski F-Score

8

Altman Z-Score

3.77

Return on Invested Capital (ROIC)

17.57%

Current Ratio

0.91

Quick Ratio

0.71

Net Debt to EBITDA

1.28

Interest Coverage

8.12

Gross Profit margin

79.71%

FCF PER SHARE

$5.00

REVENUE PER SHARE

$39.27

Gainseekers Quantitative Analysis

Summary

AstraZeneca’s valuation presents a compelling narrative of potential mispricing. With a DCF value towering over its snapshot price, the market seems to undervalue its intrinsic worth. The Forward P/E of 11.21 suggests a growth story not fully appreciated, while the robust Altman Z-score of 3.71 indicates financial stability. Despite a modest earnings yield of 3.61%, the company’s strong fundamentals and growth prospects paint a picture of resilience and opportunity.

AI Exposure / Tech Reliance

In the rapidly evolving healthcare sector, AstraZeneca is well-positioned to leverage AI and modern technologies. The drug manufacturing industry is increasingly integrating AI for drug discovery and personalized medicine, areas where AstraZeneca can capitalize on its robust R&D capabilities. This adaptability ensures it remains at the forefront of innovation.

The Bull Case

For the discerning GARP investor, AstraZeneca offers a tantalizing proposition. With an impressive ROIC of 17.57% and a Piotroski F-Score of 8, the company demonstrates exceptional capital efficiency and operational health. Its operating margin of 23.53% and a solid FCF yield, despite being modest, underscore its ability to generate cash and sustain growth. These metrics reflect a company with significant pricing power and a strong competitive position.

The Bear Case

However, AstraZeneca is not without its vulnerabilities. The high Price/Book ratio of 6.12 and Price/Sales of 4.77 suggest a premium valuation that could deter value investors. Additionally, the stock's proximity to its 52-week high, with only a 12.18% distance, indicates potential overextension. The quick ratio of 0.71 also raises concerns about short-term liquidity, highlighting areas where the company must tread carefully.

Market Sentiment & Smart Money

Short Interest %

Analyst Consensus

Buy

Average Analyst Price Target

$186.67

Institutional Ownership %

1-Year Beta

0.23

Insider Buying % (6 Mo)

Distance to 52-Week High

11.86%

Distance to 52-Week Low

27.84%

EARNINGS SURPRISE %

0.39%

50-DAY SMA

$184.10

200-DAY SMA

$183.67

⚠️ Financial Disclaimer:
This content is for informational purposes only and is not financial advice. Information may be delayed or inaccurate. We may earn a commission from partner links.